Genetic Entropy presents compelling scientific evidence that the genomes of all living creatures are slowly degenerating - due to the accumulation of slightly harmful mutations. This is happening in spite of natural selection. The author of this book, Dr. John Sanford, is a Cornell University geneticist. Dr. Sanford has devoted more than 10 years of his life to the study of this specific problem. Arguably, he has examined this problem in greater depth than any other scientist. The evidences that he presents are diverse and compelling. He begins by examining how random mutation and natural selection actually operate, and shows that simple logic demands that genomes must degenerate. He then makes a historical examination of the relevant field (population genetics), and shows that the best scientists in that field have consistently acknowledged many of the fundamental problems he has uncovered (but they have failed to communicate these problems to the broader scientific community). He then shows, in collaboration with a team of other scientists, that state-of-the-art numerical simulation experiments consistently confirm the problem of genetic degeneration (even given very strong selection and optimal conditions). Lastly, in collaboration with other scientists, he shows that real biological populations clearly manifest genetic degeneration.

Dr. Sanford's findings have enormous implications. His work largely invalidates classic neo-Darwinian theory. The mutation/selection process by itself is not capable of creating the new biological information that is required for creating new life forms. Dr. Sanford shows that not only is mutation/selection incapable of creating our genomes - it can't even preserve our genomes. As biochemist Dr. Michael Behe of Lehigh University writes in his review of Genetic Entropy, "...not only does Darwinism not have answers for how information got into the genome, it doesn't even have answers for how it could remain there." Dr. Sanford has coined the term "genetic entropy" to describe this fatal flaw of neo-Darwinian theory. This fundamental problem has been something of a trade-secret within the field of population genetics, with the rest of the world largely being kept in the dark. Fortunately, this book finally discloses this very serious problem, using language that is for the most part accessible to all scholars and students having a basic understanding of biology.

This new edition of Genetic Entropy includes numerous new lines of evidence supporting Dr. Sanford's thesis. Much of this new evidence is from recently published scientific papers that are now part of the scientific literature. Genetic Entropy is a must-read for any thoughtful person who in interested in science.

Dr. Sanford ends his book by asking two questions. First, if our genome did not actually arise via the accumulation of genetic "word-processing errors" (as is claimed), how did it arise? Second, if our genomes are undergoing relentless degeneration - where can we possibly place our hope for the future?



About the author:
Dr. John Sanford has been a Cornell University Professor for more than 30 years. He received his PhD from the University of Wisconsin in the area of plant breeding and plant genetics. While a professor at Cornell, John trained graduate students and conducted genetic research at the New York State Agricultural Experiment Station in Geneva, NY.

At Cornell, John bred new crop varieties using conventional breeding and then became heavily involved in the newly-emerging field of plant genetic engineering. John has published over 100 scientific publications and has been granted several dozen patents. His most significant scientific contributions during the first half of his career involved three inventions: the biolistic ("gene gun") process, pathogen-derived resistance, and genetic immunization. A large fraction of the transgenic crops (in terms of numbers and acreage) grown in the world today were genetically engineered using the gene gun technology developed by John and his collaborators. John also started two biotech enterprises derived from his research, Biolistics, Inc., and Sanford Scientific, Inc.

John still holds a position at Cornell (Courtesy Associate Professor), but has largely retired from Cornell and has started a small non-profit organization, Feed My Sheep Foundation (FMS). Through FMS, John has conducted research in the areas of theoretical genetics and bioinformatics for the last 14 years. This book was the "first fruits" of those efforts