Textbook in PDF

Computational cell biology courses are increasingly obligatory for biology students around the world but of course also a must for mathematics and informatics students specializing in bioinformatics. This book, now in its second edition is geared towards both audiences. The author, Volkhard Helms, has, in addition to extensive teaching experience, a strong background in biology and informatics and knows exactly what the key points are in making the book accessible for students while still conveying in depth knowledge of the subject.About 50% of new content has been added for the new edition. Much more room is now given to statistical methods, and several new chapters address protein-DNA interactions, epigenetic modifications, and microRNAs.

Contents
Networks in Biological Cells 
Structures of Protein Complexes and Subcellular Structures 
Analysis of Protein–Protein Binding
Algorithms on Mathematical Graphs 
Protein–Protein Interaction Networks – Pairwise Connectivity 
Protein–Protein Interaction Networks – Structural Hierarchies 
Protein–DNA Interactions 
Gene Expression and Protein Synthesis 
Gene Regulatory 
Regulatory Noncoding RNA
Computational Epigenetics
Metabolic Networks
Kinetic Modeling of Cellular Processes
Stochastic Processes in Biological Cells 
Integrated Cellular Networks