Ashoke (Irfan Khan) e Ashima (Tabu) são jovens indianos que têm seu casamento arranjado, seguindo as tradições locais. Eles deixam Calcutá rumo a Nova York, onde iniciam uma nova vida e se conhecem melhor. Logo eles têm um filho, Gogol (Kal Penn), nome dado em homenagem ao famoso autor russo. Ao crescer Gogol passa a buscar sua própria identidade, tendo que lidar com as tradições de sua família e seu direito de nascença americano. Ele passa a rejeitar seu próprio nome e namora Maxine Ratliff (Jacinda Barrett), uma garota rica. Enquanto planeja cursar arquitetura em Yale, Gogol se afasta cada vez mais das tradições da família. 


   While traveling by train to visit his grandfather in Jamshedpur, Calcutta born, Bengali-speaking Ashoke Ganguli meets with fellow-traveler, Ghosh, who impresses upon him to travel, while Ashoke is deep into a book authored by Nicholai Gogol. The train meets with an accident, and after recuperating, Ashoke re-locates to America, settles down, returns home in 1977 to get married to aspiring singer, Ashima, and returns home to New York. Shortly thereafter they become parents of a boy, who they initially name Gogol, and a few years later both give birth to Sonia. The family then buy their own house in the suburbs and travel to India for the first time after their marriage. The second time they travel to India is when Gogol and Sonia are in their late teens, and after a memorable visit to Kolkata and then to the Taj Mahal, they return home. Gogol falls in love with Maxine Ratliff and moves in with her family, while Ashoke spends time traveling, and Sonia moves to California, leaving Ashima all her by herself. The Ganguli family will be destined to travel to India again soon - this time under very different circumstances - and after all have endured life-changing events.


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